When a foot is rolled by a wheel, the first step should be to perform a local X-ray to exclude fractures, and if it is clear that it is a fracture, further effective external fixation should be performed. In case of combined nerve and vascular injuries, further surgical exploration and internal fixation are required. For simple soft tissue injuries, ice should be applied after the injury, and the limb should also be elevated to promote venous blood return. After soft tissue injury, secondary infections and inflammatory reactions are likely to occur and should be combined with anti-infective treatment, and if the condition allows, intravenous anti-infection can also be chosen by applying broad-spectrum cephalosporin intravenous input. It is necessary to prevent complications after trauma, because many patients are prone to complications of lower limb venous thrombosis after injury. While elevating the limb, active exercise of gastrocnemius contraction should also be performed, which can also prevent the occurrence of this disease, and regular ultrasound examinations are required.