The treatment of popliteal cyst of knee joint can be divided into general treatment, drug treatment, puncture and fluid extraction and surgical treatment. 1. General treatment: after popliteal cysts appear, it is necessary to take proper rest, avoid standing for a long time, long-distance walking, and elevate the lower limbs when resting, which is conducive to the reduction of swelling. 2. Drug treatment: drugs can be injected into the popliteal cyst, such as cortisone to reduce inflammation and pain. 3. Puncture and fluid extraction: If the popliteal fossa is obviously swollen and has a lot of fluid, the fluid in the cyst can be extracted under the guidance of ultrasound. 4. Surgery: If conservative treatment is not effective, and the popliteal cyst is large and the pain in the popliteal fossa is more obvious, it can be surgically removed. If the popliteal cyst in the knee joint continues to be unrelieved, it is recommended to consult a doctor in time and choose the appropriate treatment plan under the guidance of the doctor.