Since many hormones in the body can affect the elevation of blood sugar, like glucagon tumor causing elevated blood sugar, it is a tumor in the pancreas, if the tumor is cut out, it can be treated, and the focus is on treating the original disease. For example, acromegaly and gigantism are both caused by excessive growth hormone, which are adenomas in the anterior pituitary gland, and can be treated with surgery and radiotherapy, and octreotide can be used as an adjunct to treatment. In short, secondary diabetes has to be treated first for the primary disease. As for other diseases, the most common one is cortisolism, which causes blood glucose disorder or increased blood glucose and can be treated with insulin. Moreover, the diseases that cause cortisol increase should also be treated, such as pheochromocytoma, aldosteronism and hyperthyroidism, all of which may cause blood glucose increase. If the primary disease improves after treatment, the blood glucose will come down, such as prolactinemia and lactinemia, which are treated with bromocriptine. There are also multiple endocrine tumors that cause abnormal hormone secretion, which can cause hyperglycemia. In short, no matter what kind of hormone level increase is caused, the original disease should be treated in combination with the original disease, and after the original disease is treated, blood sugar is not a problem. The most important thing is the diagnosis and treatment of the primary disease. For secondary diabetes, the primary disease is usually treated; for hormones that cause increased cortisol, insulin can be used in addition to the treatment of the primary disease. In short, after treating the primary disease, the problem of high blood sugar will be solved.