If there is no obvious symptom for over 20 years, if the liver function test and hepatitis B virus are negative, there is no need for treatment and regular review; however, if there is liver function damage and high quantitative hepatitis B virus, treatment is generally needed. If there is no symptom, it doesn’t mean that there is no liver function damage, so you need to check your liver function regularly, and pay attention to not overworking, prohibit alcohol, don’t take drugs with liver damage, eat more fruits and vegetables, etc. If there is transaminase in the liver function test, you need to check your liver function regularly. If the liver function test shows abnormal elevation of transaminase, which cannot be relieved by itself, or if the DNA of hepatitis B virus is positive, it is necessary to treat against hepatitis B virus infection and use antiviral drugs such as entecavir. If there is no obvious symptom for more than 20 years, you can follow up regularly, and seek medical treatment when abnormalities occur, and relevant drugs should be used under the guidance of a doctor.