Advanced liver cancer can be treated with Chinese herbal medicine, but as an adjuvant treatment, it is not recommended to apply Chinese herbal medicine alone to treat it. However, patients with advanced liver cancer should try to cooperate with the treating physician’s opinion, such as chemotherapy, ascites discharge, correction of electrolyte disorder, anti-infection, and correction of hypoproteinemia, to carry out comprehensive treatment, and should not blindly and singularly use drugs or treatment. Patients with advanced hepatocellular carcinoma are often weak or have common complications, such as gastrointestinal bleeding, hepatic encephalopathy, spontaneous peritonitis, electrolyte disorders, etc., so they must be treated and analyzed comprehensively, and traditional Chinese medicine can be taken appropriately, but never apply too many drugs to avoid aggravating the burden on the liver.