Type 1 diabetic patients need to be treated with insulin once diagnosed. 2. Type 2 diabetic patients should also be treated with insulin when the following conditions occur: Tian Yong, Endocrinology Department, Zhengzhou People’s Hospital, Zhengzhou City, China 1. regular adequate oral hypoglycemic drugs, but still poorly controlled blood sugar; 2. oral hypoglycemic drugs can satisfactorily control blood sugar, but can not adhere to the drug because of side effects; 3. complications of liver and kidney insufficiency; 4. ketosis Acute complications of diabetes such as ketosis; 5. The body is in a state of stress (such as severe trauma, major surgery, serious infection, etc.); 6. Gestational diabetes mellitus or diabetes mellitus combined with pregnancy; 7. The type of unknown and obvious wasting. Recently, it is advocated that patients with high blood glucose who are first diagnosed with diabetes can be given short-term (about two weeks) insulin intensive therapy at the beginning. The reason is: early intensive insulin therapy can reverse or even repair the function of the patient’s islets, so that the patient can expect to control blood glucose in the normal range for several years afterwards without taking any hypoglycemic drugs, just by diet therapy, etc.