In the clinical treatment of membranous nephropathy, glucocorticoids combined with immunosuppressants are mainly used, in addition, monoclonal antibody therapy can also be used alone. At the same time auxiliary anticoagulation, lipid regulation, diuretic swelling and other treatments. The commonly used glucocorticoid is prednisone acetate, and the commonly used immunosuppressant is cyclophosphamide, tacrolimus and so on. Through sufficient quantity and course of standardized treatment, most of the membranous nephropathy will have good therapeutic effect in general. Some patients with poor treatment effect or even renal insufficiency, or recurrent recurrence, need to do renal puncture again to clarify the pathological type, for most of the membranous nephropathy immunosuppressant will play a good therapeutic effect, and if necessary, can use rituximab treatment. The above drugs should be applied under the guidance of doctors. Of course, there are a few patients who are not sensitive to the medication and can progress to uremic stage. Then hemodialysis or peritoneal dialysis treatment is needed. Membranous nephropathy is a pathological type belonging to nephrotic syndrome. It is usually diagnosed by renal biopsy, and in clinic, the pathological type of membranous nephropathy is divided into 4 stages. Among them, stage 1 and stage 2 have better therapeutic effect, while stage 3 and stage 4 have poorer prognosis. Clinical treatment needs to be combined with the actual situation of the patient to formulate an individualized treatment plan. At the same time, it is necessary to assist anticoagulation (such as rivaroxaban, warfarin), lipid regulation (atorvastatin calcium), diuretic swelling (furosemide, etc.) and other comprehensive treatment, and to pay attention to the rest of the life, avoiding exertion, avoiding infections, low-salt, low-fat, high-quality protein diet, and be careful to use nephrotoxic drugs. Membranous nephropathy patients are advised to go to regular hospitals, follow the doctor’s instructions to standardize the treatment, and not to use drugs without authorization.