Chest pain caused by sneezing may be due to costochondritis, pleurisy, cardiac neurosis, pneumonia, and the cause of the disease should be identified in a timely manner. 1. Costal chondritis: Costal chondritis is caused by infection or other factors, which is mostly manifested by symptoms such as enlargement of cartilage area and localized pain. When the patient sneezes, it may cause some stimulation to the rib cartilage, causing chest pain. 2. Pleurisy: usually related to trauma, bacterial infection and other factors, inflammatory mediators will stimulate the pleura to thicken and cause pain, the main clinical symptoms manifested as chest pain, chest tightness and shortness of breath, cough and other symptoms, when sneezing, the chest pressure increases, which may stimulate the pleura to cause chest pain. 3. Cardiac neurosis: because of genetic factors, environmental factors and other reasons lead to patients with a diversity of cardiovascular symptoms, generally manifested as palpitations, shortness of breath, precordial pain and so on, and accompanied by obvious depression, anxiety and other emotions. Patients may cause cardiovascular abnormalities when sneezing, which may lead to chest pain. 4. Pneumonia: generally due to bacterial infection, decreased immunity and other factors lead to inflammatory changes in lung tissue, massive reproduction of bacteria and secretion of a large number of inflammatory mediators. When the patient sneezes, the chest pressure increases, and the inflammatory mediators stimulate the pleura, which may cause sneezing chest pain. However, other factors can not be ruled out, it is recommended to consult a doctor in a timely manner, by the doctor to clarify the cause of the disease, and then give targeted treatment.