What is the problem with cream allergy? Clinically this problem belongs to contact dermatitis. contact dermatitis is divided into two cases: i. primary irritation and contact with allergens. creams themselves are strongly irritating or toxic, and anyone who comes into contact with them can develop the disease, with the following common features: 1. anyone can develop the disease after using creams. 2. there is no incubation period. 3. lesions are mostly confined to the area where the cream is applied, and the boundaries are relatively clear. The rash can subside after contact is stopped. The rash can subside after stopping contact. 2. contact allergic reactions, the cream itself is not irritating or toxic, most people do not develop the disease after contact, there are common characteristics: 1. there is a certain latent period, the first contact does not occur after the reaction, after 1-2 weeks, if the same cream again will develop. 2. the lesions are often widespread, symmetrical distribution, easy to recur.