Enlargement of the thyroid gland with multiple patchy, slightly hypodense shadows and nodular calcified hyperdense shadows needs to be considered as a nodule or tumor, and the severity needs to be determined based on the specific diagnostic findings. 1. Nodules: When multiple thyroid nodules are present in the thyroid gland, it will lead to the appearance of patchy, slightly low density shadows or localized calcified lesions on imaging. Thyroid nodules can be graded according to TIRADS to choose whether further fine-needle aspiration examination is needed. In general, patients with benign nodules, not accompanied by compression symptoms, can be followed up regularly. 2. Tumor: If the tumor is thyroid tumor, it will also lead to nodular calcified high-density image with obvious volume increase. Fine needle aspiration biopsy or surgical pathology biopsy is recommended to determine whether the tumor is malignant. If a malignant thyroid tumor is present, early surgical resection is recommended. After the thyroid gland has increased in size or imaging abnormalities, it is important to go to the hospital for further diagnosis and choose the appropriate treatment plan under the guidance of the doctor.