Cirrhosis is decompensated and can be treated with general supportive therapy, medications such as lamivudine, metadoxine, spironolactone, and surgery. Specific should follow the doctor’s instructions. 1. General supportive treatment: suggest patients to take bed rest, light, low-fat, low protein diet, strengthen nutritional support, ensure enough calorie intake, and give intravenous nutrition when necessary. Strengthen nursing care to prevent bedsores, lung infections, urinary tract infections and so on. 2. Drug treatment: Aiming at the cause of liver cirrhosis, actively control the primary disease, such as liver cirrhosis caused by Hepatitis B virus, take antiviral treatment as the mainstay, such as oral lamivudine tablets, adefovir tablets and so on; the treatment of alcoholic cirrhosis is mainly based on abstaining from alcohol, taking medicines such as Metadoxine and so on. 3. Symptomatic treatment: Cirrhosis of the third stage of failure to compensate for the abdominal cavity will usually appear. The treatment of peritoneal effusion includes sodium and water intake restriction, spironolactone and other diuretics, intravenous albumin infusion, and peritoneal puncture and drainage. 4. Surgical treatment: Cirrhosis of the third stage of decompensation, can be considered to take surgical treatment, the operation is not to remove the diseased liver, but symptomatic treatment of various complications. Cirrhosis loss of compensation of the third stage of the patient should follow the doctor’s instructions to actively cooperate with the doctor’s treatment, do not self-medication, so as not to delay the condition.