Needle eye pain of rabies injection may be a normal reaction after vaccination, or it may be caused by infection, allergy, etc., according to the specific reasons for targeted treatment. 1. Normal reaction: Because the tip of the needle will have some damage to the local skin after the rabies injection, usually in the early stage of the injection, there may be soreness in the eye of the needle. This is normal, and the pain can be relieved after a period of time. 2. Infection: When the needle eye is infected after rabies injection, the stimulation of germs can lead to local skin redness, swelling, pain and other symptoms. In this case, you need to use iodine povidone to disinfect it and use sterile gauze to bandage it. After the infection of pus, need to go to the hospital to drain the pus, to avoid aggravation of the infection. 3. Allergy: After the rabies vaccine, if there is an allergy to the drug, it can not only lead to the symptoms of needle eye pain, but also lead to local skin itching, redness and swelling and other symptoms. The symptoms are mild and usually do not require special treatment. If the symptoms are more serious, or even chest tightness, laryngeal edema and other abnormalities, it is recommended to follow the doctor’s instructions in a timely manner to use dexamethasone sodium phosphate injection, injection of methylprednisolone sodium succinate and other medications, to play an anti-allergic role. Rabies injection needle eye pain symptoms persist or aggravate the situation, need to go to the hospital in time for examination and treatment, the use of drugs should be carried out under the guidance of the doctor.