Glucagon is a hormone secreted mainly by the alpha cells of the pancreas. Glucagon, as the name implies, is the hormone that raises blood sugar, the opposite of insulin. Glucagon has a strong role in promoting glycogenolysis and gluconeogenesis, causing a significant increase in blood glucose. Gluconeogenesis is enhanced because the hormone accelerates the entry of amino acids into hepatocytes and activates the enzyme system related to the gluconeogenesis process. Glucagon also activates lipase, which promotes the decomposition of fat, and at the same time enhances the oxidation of fat and increases the production of ketone bodies, so the main role of glucagon is to raise blood sugar.