Atrophic gastritis can be treated mainly by correcting the cause and controlling the symptoms, including medication and general treatment. In addition, atrophic gastritis is a pre-cancerous state of the stomach, so it is recommended to improve gastroscopy, and for those with intestinal epithelial hyperplasia, close monitoring is needed. 1. Helicobacter pylori infection: Helicobacter pylori infection is a common cause of the disease, which can be treated by a quadruple regimen containing bismuth. The quadruple regimen includes one proton pump inhibitor, two antibiotics, and one bismuth, such as omeprazole+clarithromycin, amoxicillin+bismuth potassium citrate. 2. duodenal-gastric reflux: it is treated by protecting gastric mucosa and improving gastrointestinal dynamics. Proton pump inhibitors, such as omeprazole, ranitidine, etc., can be used to inhibit the secretion of gastric acid and reduce the damage of gastric mucosa by gastric acid; gastrointestinal dynamics-promoting medicines, such as domperidone, can be used to promote intestinal peristalsis and reduce reflux. 3. Drugs and poisons: non-steroidal anti-inflammatory drugs, such as aspirin, is a relatively common cause of gastric injury, the drugs will destroy the protective effect of the gastric mucosa, damage to the gastric mucosa, at this time it is recommended that aspirin be discontinued; and the most common poisons are alcohol, a large amount of alcohol abuse will also destroy the gastric mucosa, causing damage, it is recommended to stop drinking. 4. Autoimmune: If the body produces antibodies against the cells of the stomach lining and internal factors, it will cause the gastric glands to atrophy, vitamin B12 can not be absorbed, and ultimately lead to gastritis, pernicious anemia and so on. This is usually treated by supplementing with multivitamins. 5. Age: with age, the gastric mucosa will gradually atrophy, resulting in atrophic gastritis. Firstly, the above causes should be excluded and proton pump inhibitors should be used. Gastroscopy can find out whether atrophic gastritis is accompanied by intestinal epithelial hyperplasia, and those who are accompanied by hyperplasia need to have gastroscopy rechecked regularly under the guidance of physicians. Those with severe atrophy accompanied by severe intestinal epithelial atypical hyperplasia or hyperplasia need to be highly vigilant and closely followed up because of the increased possibility of cancer. Patients with chronic atrophic gastritis need to consult regular hospitals in a timely manner for further diagnosis and treatment under the guidance of gastroenterologists, and should not use medication on their own to delay their condition.