NGF brain neuromodulation is that NGF has an important regulatory role in the growth, development, differentiation, regeneration and function of brain nerves. NGF, or Nerve Growth Factor, is a protein with dual biological functions of brain cell nutrition and synapse growth to maintain neuron survival, and exists in tissues such as brain, ganglion, heart, placenta and other tissues, as well as in cells such as skeletal muscle, smooth muscle, Schwann cells and other cells, and regulates brain cells at all times. According to current research, this nerve growth factor has three subunits of α, β and γ, with the β subunit playing a major role. It mainly relies on the retrograde axoplasmic transport of nerve cells to absorb and play a role. Clinically, similar drugs such as rat nerve growth factor have been developed for nerve cell repair and regeneration treatment.