Age spots belong to degenerative changes of the skin in old age, which are related to natural aging, hereditary factors, sunlight damage and other factors. Common methods for removing age spots on the hands include medication, physical therapy, etc. The specific method for removing age spots on the hands should be determined by the doctor according to the specific condition, physical condition, and so on. Generally, age spots on the hands will not affect the health of the body, so there is no need for treatment. However, for those who have the need for treatment, vitamin E can be applied as prescribed by the doctor, which helps to lighten the age spots, and vitamin C can also be taken orally, which is also effective in reducing the deposition of lipofuscin. Medications such as chlorpromazine, glutathione and cysteine can also be used. In addition, physical treatments such as laser treatment, electrocautery treatment, cryotherapy and chemical peeling are also effective in removing age spots on hands. Patients with age spots on hands should choose regular medical institutions for consultation and treatment, and at the same time, they should strengthen the management of skin in daily life, keep the skin clean, avoid excessive exposure to sunlight, and go out to do a good job of sunscreen, etc., which can help prevent the occurrence of age spots.