Anemia can cause hypothermia, but not every patient with anemia will develop hypothermia. Anemia is a clinical syndrome that occurs when the volume of red blood cells in the peripheral blood is lower than normal. Anemia can be seen in a variety of diseases. Regardless of the etiology, anemia can lead to dysfunction of certain organs of the body, especially for the central nervous system. If anemia is chronic over a long period of time, it may lead to dysfunction of the central nervous system, which can lead to a rise in the body’s thermoregulatory point and can cause mild hypothermia. For patients with mild hypothermia, when the anemia improves, the patient’s symptoms of hypothermia will gradually be relieved. In clinical practice, hypothermia caused by anemia is commonly seen in adolescents, whose central nervous system is not well developed and stable enough, and mild anemia can cause mild dysfunction of the central nervous system, leading to hypothermia.