Abdominal distension with generalized weakness may be caused by gastrointestinal diseases, liver diseases, congestive heart failure and other diseases, it is recommended to consult a doctor in time. 1. Gastrointestinal diseases: such as gastrointestinal infections, inflammatory bowel disease, chronic gastritis, gastric cancer, etc., can cause abdominal distension with general weakness, and the patient may also be accompanied by epigastric pain, belching, acid reflux, emaciation, anemia, fever and other uncomfortable symptoms. 2. Liver diseases: such as hepatitis, liver cirrhosis, liver cancer, etc., in addition to the symptoms of abdominal distension and generalized weakness, patients may also have the symptoms of right upper abdominal pain, jaundice, lack of appetite, emaciation, malnutrition and other discomforts. 3. Congestive heart failure: mainly seen in right heart failure, due to long-term gastrointestinal stagnation leading to abdominal distension, due to impaired cardiac function, the patient is often accompanied by generalized weakness. Patients with abdominal distension accompanied by generalized weakness should seek medical attention in a timely manner, follow the doctor’s instructions to identify the cause of the disease and carry out the appropriate treatment, to avoid blind judgment, in order to avoid delaying the condition.