Deep infiltrating endometriosis (DIE) belongs to the more severe pathological types of endometriosis.
DIE is the infiltration of endometrial lesions ≥5 mm in depth, and common sites include the uterosacral ligament, recto-uterine trap, and vaginorectal septum, but can also be found in the rectal or colonic wall, bladder wall, and ureters.
Deep invasive endometriosis can cause symptoms such as dysmenorrhea, chronic pelvic pain, painful intercourse or postcoital pain, infertility and gastrointestinal symptoms (painful bowel movements) and urinary symptoms (hematuria, painful urination) associated with the menstrual cycle.
Currently, the treatment of endometriosis disease advocates long-term management, such as drug therapy is safe and effective recommended for long-term use, if the above symptoms are recommended for timely treatment in gynecological clinics.