ABO hemolytic disease threatens the health of newborns. Early prevention and treatment is conducive to reducing the damage of ABO hemolytic disease to newborns, promoting the healthy growth of children, and reducing the mortality rate, and the specific measures are as follows: 1. If the mother-to-be is of type O blood, and the father-to-be is of type A, B, or AB blood, the fetus should be considered to be at risk of ABO hemolytic disease, and it is necessary to go to the hospital as early as possible to conduct a prenatal blood group serological It is necessary to go to the hospital for prenatal blood serology examination as soon as possible. If the activity of antibody is not high, you can prepare for pregnancy without worry, if the activity of antibody is very high, you can reduce the antibody through medication; 2. If the baby is already conceived, the pregnant woman should start from about 16 weeks to test the antibody in the blood on a regular basis, usually once every 4 weeks, to pay close attention to whether the baby has the possibility of hemolytic disease; 3. After the birth of the newborn baby, the bilirubin should be monitored at an early stage, and phototherapy should be carried out in time after reaching the standard of phototherapy. Carry out phototherapy.