Toothache usually does not require anti-inflammation before treatment. For normal adult permanent teeth, toothache is usually caused by pulpitis or periapical inflammation, which requires emergency treatment. If it is acute pulpitis, the pulp will be opened under local anesthesia first. If it is acute apical periodontitis, the pulp is usually opened under local anesthesia to establish a drainage channel. If an acute apical abscess or alveolar abscess has formed, local drainage under local anesthesia should be carried out to reduce the pressure inside and reduce the patient’s pain. Therefore, when a toothache is usually treated urgently, it is less recommended that the patient be anti-inflammatory before treatment.