Large and small eyes may be caused by congenital developmental abnormality, or it may be caused by acquired injury to the upper eyelid muscle abnormality of the eye, from the appearance of the eyes look big and small. The patient should go to the hospital to improve all aspects of the examination, according to different causes to take different measures. 1. Congenital causes: congenital developmental abnormalities lead to ptosis, mild patients can choose the upper face levator muscle folding surgery, moderate and severe patients need to choose the upper face levator muscle shortening surgery or combined fascial sheath correction. Patients with upper eyelid muscle weakness and poor results after upper face levator muscle shortening or recurrence can choose frontalis muscle flap suspension or broad fascia suspension. 2. Acquired causes: including trauma, facial paralysis, eye infections lead to the appearance of large and small eyes, you can first carry out drug treatment, mainly to the nutrition of the nerve is the main focus, using methylcobalamin, injection of murine nerve growth factor and other drugs for treatment; if the drug treatment is not effective, then need to be corrected through surgical help, scarring or traumatic injury caused by large and small eyes are mostly through surgical methods to improve. In addition, if it is due to occupying lesions in the eye socket, such as hemangioma, etc., it can also lead to the appearance of large and small eyes. In this case, we must first actively treat the primary disease, and only then can we improve the large and small eyes. When the eye size situation is obvious, it is recommended to consult a doctor as soon as possible for examination and treatment, and the medication should be used in accordance with the doctor’s prescription, do not self-medication.