In a routine urine test, if the test report shows two plus negative urine occult blood, it indicates that the patient has a hemorrhagic lesion in the urinary system. Two plus signs are the actual measurement value of the patient, and negative is the normal reference value. Therefore, two plus negative urine occult blood refers to the presence of occult blood during the urine test of the patient, and the actual measurement value of two plus signs and the reference value of negative is an abnormal condition that requires further examination to confirm the cause. Usually, two plus urine occult blood is caused by infectious disease, stone disease, or tumor disease, traumatic disease are possible, need to carry out ultrasound or CT examination of the urinary system to clarify the presence of urinary stones, tumors, contusions caused by trauma, etc., also need to carry out urine culture test to exclude the presence of infectious lesions.