Postmenopausal discharge in the underwear is considered to be related to urine leakage, gynecological inflammation such as vaginitis and pelvic inflammatory disease, and organic diseases such as endometrial lesions. 1. Leakage of urine: As women go through the process of pregnancy and childbirth, the pelvic floor tissues have different degrees of damage; meanwhile, due to ageing and muscle atrophy, women are prone to involuntary outflow of urine when they laugh or walk fast, which leads to secretion in the underwear. 2. Gynecological inflammation: for postmenopausal women, due to the decline in the level of estrogen in the body, the vagina lacks the protection of estrogen, which can easily lead to the propagation of pathogenic bacteria, vaginitis, pelvic inflammatory disease and other gynecological inflammatory diseases, the increase in local inflammatory exudate will appear pus secretion. 3. Endometrial lesions: For menopausal women, if there is irregular vaginal discharge, we should be alert to the occurrence of endometrial cancer, the cause of which is still unclear, and patients mostly show the foul-smelling liquid or a small amount of bloody liquid outflow. For postmenopausal women with discharge in their underwear, it is recommended that they go to the gynecology department of regular hospitals to improve the ultrasound and other relevant examinations to clarify the cause of the disease and then actively treat it.