Cesarean section after three times and then pregnant again a short time can follow the doctor’s prescription of medical abortion. However, some conditions need to be met such as the determination of intrauterine pregnancy, exclusion of uterine scar pregnancy, no contraindications to the use of medicinal abortion drugs. After cesarean section should be strictly good family planning measures, especially multiple cesarean section should pay more attention to contraception. Medical abortion can only be used as a remedy after contraceptive failure, not a form of contraception. There are a few cases of cesarean scar pregnancy after cesarean section, which refers to the pregnancy in which the pregnant egg is planted in the uterine scar after cesarean section, in which case the use of medication abortion may lead to rupture of the uterus and hemorrhage and other critical situations. In addition, medication abortion drugs are prescription drugs and must be used under the guidance of a doctor. It is contraindicated for patients suffering from cardiac and hepatic insufficiency, and for those suspected of having an ectopic pregnancy. Therefore, patients who are pregnant again after three cesarean sections are advised to seek timely medical treatment, improve relevant examinations, make a clear diagnosis under the guidance of a professional doctor, and actively deal with the situation.