Postoperative delirium after meningioma surgery is associated with, among other things, an impact on the brain’s environment, leading to acute changes in the brain such as neurotransmitter, neuroendocrine, and neuroimmune system damage. General treatment and antipsychotic medication can be used to help patients recover. 1. General treatment: Ensure sufficient rest time for patients and create a good treatment environment (e.g., day and night in the ward: sufficient light during the day, dark and quiet at night, etc.). 2. Antipsychotic medication: Patients with severe perceptual disturbances or delusions may be considered for treatment with antipsychotic medication as prescribed by the doctor. Commonly used antipsychotic drugs include haloperidol, which can block the dopamine receptors in the brain and has anti-hallucinatory delusion and anti-excitatory agitation effects. It is contraindicated in patients with myelosuppression, glaucoma and Parkinson’s. Adverse effects include acute dystonia, dry mouth, constipation and sweating. Patients with delirium after meningioma surgery should consult their doctors in time and under the guidance of the doctor for regular treatment.