Rheumatism refers to rheumatic diseases, the cause of which is not yet fully understood, and is considered to be related to genetic and non-genetic factors. 1. Genetic factors: genetic factors and rheumatic diseases are related. Rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis and other rheumatic diseases have obvious genetic susceptibility, and the probability of developing the disease is much higher than that of the general population for those with a family history. 2. Non-genetic factors: Non-genetic factors such as the environment and infections are also related to the development of rheumatic diseases. Ultraviolet light and microbial infections such as type A beta-hemolytic streptococcal infection can lead to changes in the function of immune cells, resulting in immune disorders, which can lead to the disease. It is recommended that when patients suspect rheumatic diseases, they should go to the rheumatology and immunology department of the hospital in time and cooperate with the doctor for examination and treatment.