The causes of irregular shaking of the left hand with head shaking include physiologic and pathologic, and the pathologic factors include idiopathic tremor, Parkinson’s disease, etc. The treatments include medication and surgery. 1. Physiological factors: long-term mental stress, anxiety and depression, late night, lack of sleep, shock and other factors may lead to the symptoms of hand and head shaking. Active physical exercise, good habits of work and rest, and maintaining a good state of mind can effectively alleviate the symptoms. 2. Pathological factors (1) Idiopathic tremor: it is a common motor disorder with autosomal dominant inheritance. It often starts from bilateral upper limbs, starting with the hands and gradually affecting the head and neck, lower limbs, etc. Patients may have hand tremor, head shaking, abnormal gait, etc. The patient can take medication as prescribed by the doctor. Medications such as propranolol, nimodipine, etc. can be taken as prescribed by the doctor. When conservative treatment is ineffective, surgical treatment can be performed, such as deep thalamic stimulation. (2) Parkinson’s disease: resting tremor often starts from bilateral upper limbs, and may involve the head, which is obvious when resting, decreases after activities, disappears after sleeping, and aggravates when nervous. Patients can also be accompanied by bradykinesia, increased muscle tone and other symptoms. Patients can take appropriate medication as prescribed by the doctor for treatment. Irregular shaking of the left hand with head shaking may also be caused by other reasons. When patients experience discomfort, they should go to the hospital immediately. Treatment is carried out under the guidance of the doctor.