As one of the vital organs of the human body, the liver is also known as the “processing plant” because of its functions of synthesis, detoxification, metabolism, secretion, biotransformation and immune defense. When the liver is severely damaged by various factors (such as viruses, alcohol, drugs, etc.), it causes massive necrosis of hepatocytes, resulting in serious impairment or loss of compensation of the above-mentioned functions, which leads to a group of clinical syndromes mainly manifested by impaired coagulation mechanisms, jaundice, hepatic encephalopathy, ascites, etc., called liver failure. Based on the pathological histological features and the speed of progression, liver failure is divided into four categories: acute liver failure (ALF), subacute liver failure (SALF), slow-on-chronic liver failure (ACLF) and chronic liver failure (CLF). chronic liver failure (CLF). See the table below for definitions. What are the clinical symptoms of chronic plus acute liver failure? Acute or subacute liver failure based on chronic liver disease. Acute or subacute liver failure occurs within a short period of time after a previous manifestation of chronic liver disease, and the clinical symptoms are more severe than those of acute hepatitis.