High lgE does not usually heal itself. 1. lgE is serum immunoglobulin E, also known as reactin, which is one of the less abundant types of immunoglobulins in the serum. High serum immunoglobulin E needs to be treated for the disease that causes it to rise in order to bring its value down. In general, serum immunoglobulin E will not resolve spontaneously if the primary disease is not treated. 2. Increased serum immunoglobulin E is generally common in allergic diseases, such as urticaria, asthma, allergic rhinitis, etc. It may also occur in multiple myeloma, rheumatoid arthritis, tuberculosis, and atopic dermatitis, interstitial pneumonitis, eosinophilia, parasitic infections and so on. If you have high lgE, you should go to a regular hospital in time, and the doctor will determine the cause of the disease according to the specific condition, and then give the correct treatment for the cause of the disease.