The clinical appearance of sputum in the form of lumps indicates that the sputum is relatively viscous and contains less water, and is more commonly associated with respiratory diseases. It is mainly caused by infections, mainly due to bacteria, mycoplasma, chlamydia, rickettsia, and Mycobacterium tuberculosis, which cause congestion, edema, and exudation of inflammatory secretions from the airways. At this time, airway congestion is more pronounced and the water content in the airway is less, so the secretions are relatively sticky and lumpy. When inflammation irritates the airway wall, coughing and spitting out lumpy sputum occurs, CT or MRI of both lungs can be tested, and pathogen culture and drug sensitivity test can be taken from lumpy sputum to clarify the cause and treatment principles.