Women with acne at the age of 40 are mainly seen in acne, folliculitis and other diseases, the causes of which are related to endocrine disorders, poor diet and lifestyle habits, poor skin hygiene, and lowered resistance, etc. The causes of the disease are related to endocrine disorders, poor diet and lifestyle habits, poor skin hygiene, and lowered resistance. 1. Acne: When the hormone secretion level in the body is abnormal, it will affect the secretion of sebaceous glands and make the cells around the hair follicles over-keratinized, and at the same time the local infection of Propionibacterium acnes, it may induce acne. Bad dietary habits such as spicy and stimulating foods and excessive alcohol consumption, as well as bad lifestyle habits such as staying up late and not paying attention to local skin cleansing, are all triggering and aggravating factors for acne. In addition, 40-year-old women who suffer from acne need to go to the gynecology department for ultrasound or hormone level testing to rule out polycystic ovary syndrome and other diseases. 2. Folliculitis: often caused by bacterial or fungal infections and other pathogens, decreased immunity or diabetes is the main cause of folliculitis. In addition, 40-year-old women with acne may also be other diseases, such as facial disseminated milia lupus. It is recommended that the patient go to the regular hospital in time, according to the manifestation of the rash and related auxiliary examination for a clear diagnosis, and standardized treatment under the guidance of the doctor.