Hypothyroidism, or simply hypothyroidism, is a syndrome of generalized hypometabolism due to decreased synthesis and secretion of thyroid hormones or underutilization by tissues, and is more common in women than in men. It is more common in women than in men. According to the degree of hypothyroidism, it is divided into clinical hypothyroidism and subclinical hypothyroidism. Clinical hypothyroidism has obvious clinical manifestations, while subclinical hypothyroidism has no obvious symptoms and can only be detected by laboratory tests. Even at the subclinical hypothyroidism stage there are certain hazards to the body, especially in pregnant women subclinical hypothyroidism can affect the intellectual development of the fetus. The prevalence rate is still high. It is roughly 5%. The onset of this disease is insidious, the course of the disease is long, generally does not have specific clinical symptoms and signs, it is very easy to miss and misdiagnosis, some years or even more than ten years before diagnosis, if you have the following manifestations, please go to the endocrinology department to do a checkup, such as fear of coldness, fatigue, a feeling of swelling of the hands and feet, lethargy, memory loss, slow response and less sweating, hoarseness, hearing loss, pallor, facial edema, thick lips, tongue, palms of the hands and feet ginger yellow Dry skin, dry and rough, flaking, thinning hair, low skin temperature, joint pain, weight gain, slow pulse rate, abdominal distension, constipation, menstrual disorders or excessive menstruation in women. Involvement of the heart can appear pericardial effusion, heart failure, and mucous edema coma can occur in severe patients. Hypothyroidism in pregnancy can lead to fetal mental retardation, and is also associated with gestational hypertension, placental abruption, spontaneous abortion, fetal distress, preterm labor, and the occurrence of low birth weight babies. It is particularly important to note that some experts advocate routine screening for TSH in pregnant women for timely detection and treatment. Some scholars advocate pre-pregnancy screening for those at high risk of developing hypothyroidism.