Irbesartan Hydrochlorothiazide Tablets effects in men include dizziness, nausea, vomiting, abnormal urination, and fatigue, but the effects of this product are not gender specific. Irbesartan Hydrochlorothiazide Tablets instructions state that the adverse effects of this product include dizziness, fatigue, nausea, vomiting, abnormal urination, elevated urea nitrogen and creatinine, increased creatine kinase, hypotension, edema, tachycardia, flushing, diarrhea, muscular or skeletal pain, rash, altered libido, and sexual dysfunction. Adverse reactions to the drug are not gender-specific and can occur in men or women. This product is used to treat essential hypertension. It is contraindicated in the 4th to 9th month of pregnancy, lactation, anuria, severe renal impairment, intractable hypokalemia, hypercalcemia, severe hepatic impairment. It should be used appropriately under medical supervision.