If there is numbness in one of the upper and lower limbs, it is usually considered to be a precursor of cerebrovascular disease.
Intracranial lesions that affect sensory conduction fibres and affect sensory function can manifest as numbness in the upper and lower limbs on the opposite side. The clinical presentation depends on the location and size of the infarct and may include numbness, weakness and speech disturbances on one side of the face or limb.
A CT and magnetic resonance imaging (MRI) of the brain can help confirm the diagnosis.