If the patient is suffering from gum swelling and pain caused by oral inflammation such as gingivitis and periodontitis, he usually needs to be treated with anti-inflammatory drugs. There are many anti-inflammatory drugs clinically used to treat gum swelling and pain caused by oral inflammation, such as cephalosporins, penicillins and erythromycins, but there are not so many as the top ten classes. Some patients may have allergies to certain anti-inflammatory drugs, and it is recommended that patients choose anti-inflammatory drugs that are suitable for them according to their own physique and condition. The more common clinical anti-inflammatory drugs for oral inflammation are cephalosporins, such as cefprozil, cefdinir, cefixime, etc. If there are patients with cephalosporin allergy, they can use amoxicillin, roxithromycin, spiramycin, penicillin and other drugs, but before using the drugs, the same need to pay attention to the presence of drug allergy. Clinical often with anti-anaerobic bacterial infection drugs for the treatment of oral inflammation, such as metronidazole class, tinidazole class, ornidazole class, the combination of drugs for the elimination of inflammation is more effective. If the patient’s pain symptoms are more serious, it is recommended that the patient with ibuprofen and other drugs with pain relief for pain relief. In addition, patients can also use some Chinese medicines, such as Niuhuang detoxification tablets, Huanglian Shangqing Pills, watermelon cream tablets, and compound herbal coral tablets to help relieve inflammation symptoms and improve gum swelling and pain. In conclusion, there are many kinds of medicines and they should be used correctly under the guidance of professional doctors.