40mg febuxostat can be broken to take, but the specific dosage is recommended that patients consult a physician. Febuxostat reduces serum uric acid concentration by inhibiting uric acid synthesis in the patient’s body, and currently there are various specifications of Febuxostat such as 20mg/tablet, 40mg/tablet, 80mg/tablet, etc. The recommended starting dose of Febuxostat is 20mg each time, so 40mg/tablet may be broken and taken. The recommended starting dose of Febuxostat is 20mg per dose, so the 40mg/tablet of Febuxostat may be broken up and taken half a tablet at a time. Since there are various sizes of Febuxostat, it is recommended that patients consult with their physician for the exact dosage and take the medication as prescribed. Common adverse reactions to the drug include liver function abnormalities, nausea, arthralgia, and skin rashes. Patients with a history of allergy to the ingredients of this product, patients undergoing treatment with azathioprine and mercaptopurine are prohibited from using this drug. Note that the safety of this product in patients with severe renal impairment has not been established due to little experience with its use and should be used with caution. Patients who had gouty arthritis prior to the use of this product should not use it until the symptoms are stabilized. Drugs need to be used under the guidance of a physician, it is recommended that patients who need to take febuxostat to the rheumatology and immunology department of a regular hospital for consultation, do not take the drug on their own.