Painful breast nodules are commonly caused by the following reasons: 1, breast hyperplasia: this is a common breast disease, patients can go to the hospital’s general surgery or breast surgery, usually need to check the mammography ultrasound. If the disease is the case, you can take oral Chinese medicine for treatment, such as prolotherapy pills, breast fetish elimination, etc. This can improve the symptoms of local pain, and some patients need to stop drinking alcohol and eating spicy food. 2, benign tumors of the breast: such as breast fibroids, you can check the mammography and mammography for clarification. If the pain is not serious, there is no need to worry too much and regular review is sufficient. 3. Malignant tumors of the breast: such as breast cancer or breast sarcoma, etc., you need to go to the hospital as soon as possible to improve the relevant examination, perform surgery to remove the tumor, and later may need to give chemotherapy and other related treatment.