Swelling and pain in the palm of the foot is considered to be related to trauma, gout, plantar fasciitis, bone fracture, etc. Patients need to follow the doctor’s instructions to use medication, physical therapy or surgical treatment to quickly reduce swelling. 1. Trauma: If it is clear that the injury is caused by trauma, the patient can achieve the purpose of reducing swelling through early ice packs and late heat packs, and the severe pain can be relieved by non-steroidal anti-inflammatory drugs such as ibuprofen and diclofenac sodium, etc., as prescribed by the doctor. Localized skin damage is large need to follow the doctor’s instructions to clean up the wound, daily attention to strengthen the skin care. 2. Gout: gout caused by swelling and pain in the palms of the feet, the acute stage can be indomethacin, etoricoxib and other non-steroidal anti-inflammatory drugs to relieve, but also colchicine treatment of the disease, prompting the disappearance of swelling. In the intermittent period of the disease, patients can follow the doctor’s instructions with allopurinol, febuxostat, benzbromarone and other drugs to control the condition, so as to relieve the discomfort. 3. Plantar Fasciitis: In the acute stage, when the patient is accompanied by the phenomenon of swelling and pain, the patient should be braked to rest, elevate the lower limbs and local ice packs, which can help relieve pain and swelling. For serious pain, external diclofenac sodium diethylamide latex, piroxicam and other drugs, but also available betamethasone, lidocaine closed treatment. If the patient’s condition is serious, plantar fascia release is feasible. 4. Fracture: If the fracture causes swelling and pain in the ball of the foot, you can use ibuprofen, indomethacin and other non-steroidal anti-inflammatory drugs as prescribed by the doctor to alleviate the problem, but also can be used to furosemide, hepcidium saponin sodium and other drugs to reduce the swelling. Depending on the degree of fracture, some patients may choose surgical treatment such as manipulation, plaster fixation, incision and reduction internal fixation or external fixation. It is recommended that people with swollen and painful feet should consult a doctor for examination, and follow the doctor’s instructions for treatment after clarifying the cause of the disease, and should not use medicines and prescriptions indiscriminately on their own, so as not to aggravate the swelling and pain.