Atrophic gastritis of the gastric antrum is usually not serious, but the disease is temporarily incurable and may become cancerous, so it needs to be diagnosed as early as possible and treated accordingly. Atrophic gastritis belongs to a type of gastritis, which refers to the changes of gastric mucosal epithelium, such as reduction of intrinsic glands, atrophy of gastric mucosal glands, and intestinal epithelial hyperplasia, etc. It is a kind of chronic gastric disease. The cause of this disease is clear, related to Helicobacter pylori infection, and autoimmune damage, disease causing gastric mucosal damage, radiation factors, genetic factors, etc. can also induce this disease. The course of this disease is long, and there may be no obvious symptoms in the early stage, and many people may have the tendency of malignant changes such as heterogeneous hyperplasia in the gastric mucosa, which may easily develop into gastric cancer after the examination of the corresponding symptoms. And the incidence of this disease is high, about 23%. Therefore, it is recommended to avoid the infection of Helicobacter pylori, actively treat the primary disease, and regularly review or physical examination. If symptoms such as abdominal pain, feeling of fullness and loss of appetite occur, the patient should consult the doctor for relevant examinations to confirm the diagnosis of the disease and follow the doctor’s instructions to carry out active and regular treatment, so as to slow down the progression of the disease and reduce the risk of cancer.