Swelling of the feet in the afternoon is mainly caused by vascular lesions of the lower limbs, such as varicose veins or thrombosis of the lower limbs, internal diseases such as heart disease, renal disease, etc., as well as hypoproteinemia caused by various reasons. 1. Lower extremity vascular lesions, the most common are varicose veins and lower extremity venous thrombosis, etc., which can be clearly diagnosed through ultrasound examination, and require surgery or anticoagulation treatment. 2. caused by internal diseases, such as heart failure, renal insufficiency, hypertension, diabetes mellitus, hyperthyroidism, etc., generally have primary diseases, mostly bilateral foot swelling, through the control of primary diseases after foot swelling will reduce or disappear. 3. Hypoproteinemia caused by various reasons, such as blood loss. The clinical causes of afternoon foot swelling are very complex, but also need to exclude physiological factors such as excessive standing leading to poor venous return of the lower limbs can also cause afternoon foot swelling, it is recommended to go to the hospital in a timely manner to diagnose and treat, to clarify the cause of the disease.