Fever after DPT5 vaccination can be reduced by decreasing clothing, increasing water intake, and using medications such as acetaminophen to reduce fever if necessary. 1. Physical cooling: Fever caused by DPT5 vaccination is commonly low-grade fever, which can be controlled by decreasing the child’s clothing, increasing indoor ventilation, lowering the room temperature to about 26℃, and increasing the child’s water intake. 2. Medication to reduce fever: If your child’s temperature is higher than 38.5℃, you can use medication such as ibuprofen or acetaminophen under the guidance of your doctor to reduce fever and cool down the temperature. After vaccination, common adverse reactions include hard nodules at the site of vaccination, redness and swelling, increased crying, fever, etc. The symptoms are generally mild, if the child has hives, repeated elevation of body temperature need to consult a doctor in time for treatment.