Whether melanoma can be cured depends on the severity of the disease and whether it is actively treated. Melanoma is a malignant tumor of cells that can produce melanin, it is a kind of malignant tumor with high degree of malignancy, usually cannot be cured completely, usually manifests that nevus appears suddenly or grows rapidly, deepens in color and has comet-shaped tumors around it, and may have local pain, infection, ulcers and so on, and it occurs in the friction palms of the hands, soles of the feet, or the neck, the upper limbs, under the fingernails, and labia, and so on. Patients with melanoma in the early stage of the disease can generally achieve clinical cure through surgical treatment, such as Mohs surgery, melanoma excision, etc. In the middle and late stages, they can only be actively treated to prolong the survival period, and the clinical cure rate is relatively low. In the middle and late stages, due to the load of the lesion is relatively large, and it is easy to have metastasis to distant organs, and the surgical excision can not achieve the radical cure. It is recommended that patients go to regular hospitals to find professional doctors for diagnosis and treatment, so as to achieve early detection and early treatment.