1. Controlling the infectious cause of optic neuritis and eliminating the underlying infection will usually stop new attacks. 2. If there is an immune disorder, such as systemic lupus erythematosus, dry syndrome, leukoaraiosis, and other causes of vasculitis, treatment of the underlying disease usually stops the patient’s relapses. 3. If the patient’s cause is multiple sclerosis, treatment of multiple sclerosis may reduce the risk of relapse (including optic neuritis attacks). Current treatment includes intravenous high-dose glucocorticoid therapy and chronic phase immunomodulatory therapy to prevent relapses. 4.If the disease is due to optic neuromyelitis optica, high-dose glucocorticoid therapy in the acute phase and subsequent long-term immunosuppressive therapy will help prevent relapse (including optic neuritis optica attacks). 5. Regular follow-up examinations, such as brain and spinal cord MRI, AQP4 antibodies or other inflammatory markers as appropriate to understand lesion activity, and a reasonable treatment plan can reduce disease recurrence 6. Regular neuro-ophthalmologic examinations to detect any signs of optic neuritis recurrence and timely adjustment of treatment 7. Take medication as prescribed by your doctor, do not change the dosage or discontinue medication at your own discretion, as this may easily lead to recurrence. 8. Some patients have cold-like symptoms before the onset of the disease, and prevention of colds may also reduce the risk of developing the disease. However, not all colds can lead to a recurrence of optic neuritis. Some vaccines may be associated with the onset of optic neuritis. Reducing or prohibiting vaccination by referring to the vaccine instructions may reduce the chance of developing the disease, so it is important to consider and weigh the pros and cons before receiving vaccination. 10. Stopping exposure to drugs or substances that are toxic to the optic nerve can help stop the onset of the disease. 11, Maintaining a healthy lifestyle, balanced nutrition, exercise, preventing obesity, maintaining emotional health, and getting adequate rest, along with avoiding toxins, such as cigarettes, can prevent relapse in many patients with the disease.