Knee pain from cold can be treated as follows: first, get out of the cold environment and try to avoid catching cold again; second, pain medication, oral anti-inflammatory and pain medication, such as meloxicam, celecoxib and loxoprofen sodium tablets; third, physical therapy, such as microwave physiotherapy or far-infrared physiotherapy, can be used to relieve pain and inflammation of the joint caused by cold. Fourth, external medication can be used, such as ointment, such as Tongluo pain relief cream for treatment, which can play a role in opening up the meridians and relieving pain, and can also be applied externally with Futalin ointment, which can also play a role in local pain relief; fifth, oral Chinese medicine, such as oral Dazhili capsule, Guiqi strong bone particles, which can also play a role in opening up the meridians and activating the meridians. This can also play a role in opening and activating the meridians and relieving pain.