Herpes zoster, commonly known as “serpentine sores”, is a skin disease caused by varicella-zoster virus infection that affects the mucous membrane and nerves of the skin. The principles of treatment are antiviral, nerve nutrition, and symptomatic pain relief. Early and aggressive scientific treatment is important to prevent and reduce post-herpetic neuralgia. Postherpetic neuralgia is defined as pain that persists for 3 months after the herpes has subsided in patients with herpes zoster. The clinical manifestations are persistent, spontaneous burning or deep pain, paroxysmal burning pain and sensory hypersensitivity and unbearable itching. It is commonly seen in middle-aged and elderly people, with an incidence of 50-75% in elderly patients with herpes zoster over 60 years of age. The clinical symptoms are severe, the treatment is difficult, and the quality of life of patients is seriously affected. The aims of treatment are: (1) To relieve pain. (2) To improve sleep. (3) To improve the quality of life. There are many treatment methods for postherpetic neuralgia, mainly including local medication, systemic medication, nerve block, physical therapy and Chinese herbal medicine. (1) Systemic therapy: application of non-steroidal anti-inflammatory drugs, opioids, antidepressants, antiepileptics, sedatives and neurotrophic drugs, etc. (2) Local therapy: local anesthetics, topical non-steroidal drugs and capsaicin preparations, etc. (3) Nerve block therapy: stellate ganglion block, epidural block, paravertebral nerve block. (4) Physical therapy: microwave, ultrasound, ultraviolet light, red light irradiation and laser, etc. (5) Traditional Chinese medicine therapy: oral administration of traditional Chinese medicine, acupuncture treatment, cupping therapy.