A macular thickness of 512×128 in both eyes refers to a macular thickness of 512 μm and 128 μm in both eyes, and the patient may have macular or intracranial pathology. Under normal circumstances, the retinal thickness of the macula centrale is approximately 173 ± 13 μm, and the reference range is between 148 and 198 μm, taking into account that this value varies from one population to another. If this range is exceeded, the patient has an abnormal macular thickness. A macular thickness of 512 μm in one eye indicates macular thickening, which may be related to macular degeneration, intracranial pathology, and other diseases. The patient may have macular edema, the patient needs to go to the ophthalmology department of the hospital in a timely manner for examination, to clarify the cause of the disease, and then carry out targeted treatment. It is recommended that patients with macular degeneration consult a doctor in a timely manner to assess their condition and follow the doctor’s instructions for treatment.