Albumin transaminase 135U/L is on the high side, the normal range for women is 5~35U/L and for men is 5~40U/L. Whether it is serious or not cannot be generalized, but needs to be considered according to the specific cause of the disease, the progress of the disease and other aspects. Elevated ALT may be caused by liver and gallbladder diseases, drug factors or other diseases. 1. Liver and gallbladder diseases: acute viral hepatitis, cirrhosis, liver cancer, etc. can lead to the elevation of ALT, and if there is no active treatment and the disease progresses, the condition will be more serious. Cholecystitis, fatty liver, alcoholic hepatitis and other diseases can also cause ALT elevation, relatively speaking, the condition is mild, and can be relieved after active treatment. 2. Drugs: If you take drugs with hepatotoxicity, it may also lead to the elevation of ALT. Usually, it can be relieved after stopping the medication, and the condition is not serious. 3. Other diseases: pancreatitis, pulmonary infarction, renal infarction, dermatomyositis and other diseases can also lead to ALT elevation. If not actively treated, the condition will further deteriorate and may lead to serious consequences. It is recommended that patients with elevated ghrelin seek timely medical attention, complete the relevant examinations, clarify the cause of the disease under the guidance of a professional physician, and actively carry out treatment.