Pulmonary atherosclerosis is mainly treated by lipid-regulating drugs, antiplatelet drugs, thrombolytic drugs and anticoagulant drugs. Pulmonary arteriosclerosis may be affected by dyslipidemia, which needs to be improved by diet and exercise along with regular lipid testing, and more importantly, the use of statin lipid regulating drugs, such as atorvastatin. In order to prevent blood clots from forming and causing embolization of the pulmonary arteries, antiplatelet drugs are needed, commonly used such as aspirin and clopidogrel. If the pulmonary arteriosclerosis formed thrombus, also need to use thrombolytic and anticoagulant drugs for treatment, thrombolytic drugs can be used alteplase, anticoagulant drugs commonly used warfarin and so on. It is worth mentioning that the above drugs can only slow down the progress of sclerosis, there is no drug that can reverse atherosclerosis, but can only control the development of the disease, improve the prognosis and improve the quality of life of the patients. In conclusion, there are many drugs for pulmonary atherosclerosis, but all need to go to a regular hospital, under the guidance of the doctor to take.