Before the HPV vaccine is given, women who have a history of sexual intercourse or are married must be examined to find out whether there are lesions on the cervical epithelium and whether they are highly infected with HPV before they can be vaccinated against cervical cancer. Clinically, it is recommended that the first vaccination should not be given during breastfeeding, pregnancy or menstruation, and the second is that three doses of the cervical cancer vaccine should be given within one year, and all three doses should be given within one year before the vaccine can play a preventive role. In addition, after the cervical cancer vaccination, it does not mean that 100% of the patients will not get cervical cancer. Regular clinical review is needed, and cervical cancer screening should be done once a year, because the preventive effect of cervical cancer vaccine is very high, which can reach 92%, but individual HPV infection may still occur and cause cervical cancer, so regular review is very important.